Home Pet Health and TreatmentPyometra in Dogs: Signs, Causes, Diagnosis, Treatment and Prognosis

Pyometra in Dogs: Signs, Causes, Diagnosis, Treatment and Prognosis

by Vetic Editorial
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What is Pyometra in Dogs?

Pyometra in dogs is a serious uterine infection that leads to the accumulation of pus within the uterus. It typically occurs due to bacterial invasion of the uterus of a dog after heat cycles

The condition results from hormonal imbalance in dogs that causes the uterine lining to thicken, creating an ideal environment for bacterial growth.

The bacteria release toxins that can leak into the bloodstream, causing sepsis and potentially leading to organ failure. Without immediate treatment, pyometra in dogs can be fatal.

What Causes Pyometra in Dogs?

The main causes of pyometra in female dogs include hormonal fluctuations after heat cycles and bacterial infections. During heat in dogs or estrus, progesterone thickens the uterus lining to prepare it for pregnancy. 

When this happens repeatedly without conception, the uterus can develop cysts that trap fluid, allowing bacteria to multiply. 

Hormonal imbalance in dogs and repeated exposure to estrogen or progesterone also contribute to this condition. Pyometra is most common in older, unspayed females but can affect any sexually mature dog.

My Dog is Spayed, Can She Develop Pyometra?

A correctly spayed dog will not develop pyometra because both the ovaries and uterus are removed. However, if a small portion of the ovarian or uterine tissue remains after surgery, stump pyometra can occur. This rare form of pyometra in dogs results from hormonal activity in the remaining tissue and still requires immediate veterinary attention.

What are the Signs of Pyometra?

Pyometra in dogs symptoms vary depending on whether the cervix is open or closed. Early signs of pyometra in dogs often resemble general illness, making timely diagnosis essential.
The most common pyometra symptoms include:

  • Dog lethargy and discharge
  • Loss of appetite and weight
  • Fever in female dogs
  • Excessive drinking and urination
  • Pale gums
  • Vaginal discharge or bleeding and pus from vagina

Open Pyometra vs Closed Pyometra

Behavioral and Physical Symptoms

Dogs with pyometra may appear tired, depressed, or withdrawn. You may notice behavioral changes such as refusal to eat, increased thirst, restlessness, or painful urination. 

If you observe fever in female dogs or unusual vaginal discharge, seek veterinary care immediately. In closed pyometra in dogs symptoms progress faster, often leading to sepsis.

How is Pyometra Diagnosed?

Accurate diagnosis involves physical examination, blood tests, and imaging. Since pyometra symptoms often overlap with other infections, multiple tests help confirm the condition and assess the dog’s overall health.

Veterinary Examination and Clinical Evaluation for Pyometra

During a physical exam, veterinarians evaluate capillary refill time, hydration level, body temperature, and vaginal discharge. They may also palpate the abdomen to check for uterine enlargement or pain in the lower belly.

Blood Tests Used to Confirm Pyometra in Dogs

No single test confirms pyometra, but a complete blood count helps assess infection severity. Elevated white blood cell count, high globulin levels, and signs of kidney or liver strain can indicate systemic infection.

Radiography and Imaging Tests for Detecting Pyometra

X-rays and ultrasound imaging reveal the size and condition of the uterus. An enlarged dogs womb filled with fluid suggests pyometra, though radiographs also help distinguish it from pregnancy, uterine tumors, or hydrometra.

What is the Treatment of Pyometra in Dogs?

Treatment options depend on the dog’s health, the type of pyometra, and breeding plans. The two main approaches are emergency surgery and medical management.

Emergency Surgery (Ovariohysterectomy)

Surgical removal of the uterus and ovaries is the definitive treatment for pyometra in dogs. This ovariohysterectomy eliminates the infection source and prevents recurrence.
Recovery period: 7–10 days with antibiotics and IV fluids to restore hydration and combat infection. Early surgical intervention significantly improves survival chances.

Medical Management (For Early Cases)

In mild or breeding-value cases, veterinarians may attempt medical treatment of pyometra using hormones like prostaglandins to expel uterine contents.
However, this method offers short-term relief and carries risks of recurrence. Regular monitoring is mandatory.

Medical Management and Antibiotic Therapy for Pyometra

Antibiotic treatment for pyometra is essential both before and after surgery to control bacterial infection. However, antibiotics alone cannot fully cure pyometra in dogs since pus and infected uterine tissue remain. Surgery remains the most effective long-term solution.

Is Your Dog At Risk of Developing Pyometra?

Dogs are more likely to develop pyometra if they are unspayed, middle-aged, or older than six years. Those exposed to frequent hormonal therapy or with repeated heat cycles without pregnancy are at higher risk.

Risk Indicators Checklist:

  • Female older than 6 years
  • Not spayed or incomplete spay surgery
  • Frequent false pregnancies
  • Received hormone-based fertility treatments
  • History of uterine infections

What is the Prognosis of Pyometra?

With early diagnosis and prompt ovariohysterectomy, the prognosis for pyometra in dogs is generally good. Delayed treatment, existing organ damage, or signs of sepsis worsen the outlook. In severe untreated cases, pyometra can be life-threatening within days. 

When left untreated, collapse may occur within 48–72 hours due to septic shock and organ failure.

How Can You Prevent Pyometra in Dogs?

Spaying (complete ovariohysterectomy) before a female dog’s first or second heat cycle is the most effective way to prevent pyometra. Early sterilization eliminates hormonal fluctuations and the risk of uterine infections.

Prevention of Pyometra is Early Spaying:

  1. Schedule your dog’s spay between 5–6 months of age.
  2. Avoid repeated heat cycles without breeding.
  3. Do not use unnecessary hormonal treatments or contraceptives.
  4. Maintain hygiene during and after heats.

FAQs

1. What is pyometra in dogs?

It is a life-threatening infection in the uterus of dogs that causes pus buildup and systemic illness if left untreated.

2. What are the common signs of pyometra in dogs?

Common symptoms include lethargy, vaginal discharge, fever, loss of appetite, and swelling of the abdomen.

3. What causes pyometra in dogs?

Hormonal imbalance in dogs and bacterial infection after heat cycles are the primary causes of pyometra.

4. How is pyometra diagnosed in dogs?

Diagnosis involves a physical exam, blood tests, and imaging to confirm pus and bacterial infection in the uterus.

5. What are the different types of pyometra in dogs?

There are two types: open pyometra (with vaginal discharge) and closed pyometra (sealed uterus filled with pus).

6. Can pyometra be prevented in dogs?

Yes, early spaying fully prevents pyometra by removing the uterus and hormonal source.

7. How is pyometra treated in dogs?

Treatment includes emergency ovariohysterectomy and supportive antibiotic therapy.

8. Is pyometra in dogs life-threatening?

Yes, untreated pyometra can lead to sepsis, kidney failure, and death within a few days.

9. What is the prognosis for a dog with pyometra?

With early surgery, most dogs recover well; delayed treatment can lead to complications.

10. What are the risks of not treating pyometra in dogs?

Systemic infection, organ failure, and death due to septicemia.

11. Can antibiotics cure pyometra?

Antibiotic treatment for pyometra controls infection temporarily but cannot cure it permanently without surgery.

12. Can pyometra recur after surgery?

After complete ovariohysterectomy, recurrence is not possible since the uterus and ovaries are removed.

13. Is pyometra painful for dogs?

Yes, pyometra causes severe abdominal pain, fever, and discomfort due to pus and toxin buildup in the uterus.

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