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20 Most Common Cat Diseases According to Gender, Neutering Status and Age

by Vetic Editorial
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Cats are experts at hiding illness, so most conditions are already advanced by the time cat parents notice obvious signs like not eating, hiding or lethargy. Regular veterinary checkups, timely vaccination, parasite control and neutering greatly reduce the risk of many serious diseases and complications in cats.

Common Cat Health Problems Noted by Veterinarians

Veterinarians commonly see a predictable set of health issues in cats, many of which are influenced by age, gender, neutering status and lifestyle (indoor vs outdoor).​
The most frequent problems include dental disease, obesity, urinary tract issues (UTIs and FLUTD), arthritis and joint problems, skin allergies (especially flea allergy dermatitis), hormonal diseases like hyperthyroidism and diabetes, anaemia and heart disease.​

Health Problems of Spayed Female Cats

Spayed female cats are protected from reproductive cancers and infections, but they can still develop metabolic and lifestyle-related diseases like obesity, dental disease and endocrine problems.​

They may also be predisposed to certain urinary tract diseases, post‑operative complications if surgery after‑care was poor, and stress‑related behaviours such as overgrooming.​

  1. Hyperthyroidism 
  2. Overgrooming 
  3. Flea bite hypersensitivity (dermatitis or allergic reactions to flea bites)
  4. Overgrown nails `
  5. Post-operative complications from neutering/spaying surgeries

Health Problems of Intact Female Cats

Intact (unspayed) female cats are at high risk for reproductive system infections and tumours, including pyometra, endometritis, mammary gland tumours and mastitis.​

They are also more likely to experience anaemia and malnutrition from repeated pregnancies, as well as behaviour‑linked problems like overgrooming, stress, urinary tract issues and poor body condition if not properly cared for.​

  1. Complications and infections of the reproductive system (pyometra, endometritis, mammary gland tumours)
  2. Overgrooming and skin hypersensitivity 
  3. Anorexia
  4. Anaemia 
  5. Urinary tract infections (UTIs)

Chronic Health Problems of Intact Male Cats

Male cats (intact and neutered) are particularly prone to urinary tract obstruction and FLUTD because they have a narrower urethra, making blockages more likely and more dangerous.​

They also commonly develop obesity, dental disease, arthritis and trauma‑related injuries (especially cat bite wounds in intact outdoor males), along with chronic conditions like heart disease as they age.​

  1. Periodontal disease (gum and teeth diseases)
  2. Heart murmur
  3. Weight Issues (anorexia)
  4. Cat bite injuries
  5. Urinary tract infections (UTIs) & Cystitis 

Health Problems of Neutered Male Cats

Neutered male cats are less likely to roam, fight and develop reproductive cancers, but often have a higher risk of obesity and related diseases like diabetes and arthritis if their calorie intake is not adjusted after neutering.​
They are also over‑represented in FLUTD and urethral obstruction cases, making litter‑box monitoring and rapid response to any straining or reduced urination crucial.​

  1. Obesity
  2. Periodontal diseases
  3. Lameness (joint/mobility disorders)
  4. Constipation 
  5. Cardiac dysrhythmia

What are The Initial Signs of Common Cat Health Problems?

Many early signs are subtle: reduced grooming, slight appetite changes, mild weight loss or gain, increased thirst, hiding, low activity or small changes in litter‑box habits.​

Cat parents should seek veterinary advice early for any persistent change lasting more than 24–48 hours, especially for not eating, breathing changes, straining to urinate or sudden lameness.​

1. Managing Diabetes Mellitus in Cats

Diabetes mellitus is more common in middle‑aged to older, overweight cats and can affect both males and females, including spayed females.​
Early signs of diabetes in cats include increased thirst and urination, increased or unchanged appetite with weight loss, and sometimes weakness in the hind legs; management typically involves diet changes, weight control, insulin therapy where prescribed, and regular blood glucose monitoring under veterinary supervision.​

2. Recognizing and Treating Urinary Tract Infections (UTIs)

Spayed females can still develop lower urinary tract infections and inflammation, especially if they are overweight, stressed, or on low‑moisture diets.​ 

Signs include frequent attempts to urinate, straining, vocalisation in the litter box, blood in urine, and urinating outside the litter box; treatment depends on the cause and may include antibiotics, urinary diets, pain relief and increased water intake as advised by a veterinarian.​

3. Signs and Management of Hyperthyroidism in Cats

Hyperthyroidism is common in senior cats and results from an overactive thyroid gland producing excess thyroid hormone.​

Typical signs include weight loss despite good or increased appetite, hyperactivity, increased thirst and urination, vomiting or diarrhoea, and sometimes a fast or irregular heart rate; diagnosis is confirmed via blood tests and treatment can include medication, prescription diets, radioactive iodine or surgery depending on your vet’s recommendation.​

4. Preventing and Controlling Obesity in Cats

Obesity is one of the most important risk factors for diabetes, arthritis, FLUTD and heart disease in cats.​ 

Prevention focuses on controlled calorie intake, measured feeding, avoiding high‑calorie treats, encouraging play and activity, and working with a veterinarian to create a safe weight‑loss plan if a cat is already overweight.​

5. Understanding Feline Lower Urinary Tract Disease (FLUTD)

FLUTD is an umbrella term for conditions affecting the bladder and urethra, including urinary crystals, stones, sterile cystitis and urethral plugs.​ 

Risk factors include being overweight, low water intake, stress, unbalanced diets and a sedentary indoor lifestyle; symptoms include frequent straining, passing small amounts of urine, blood in urine and licking the genital area, and complete blockage is a life‑threatening emergency needing urgent veterinary care.​

6. Recognizing and Managing Arthritis in Cats

Arthritis and degenerative joint disease are common in older and overweight cats, leading to chronic pain and reduced mobility.​

Subtle signs include reluctance to jump, stiffness after resting, reduced grooming, irritability when touched and less interest in play; management may include weight control, joint supplements, pain medication, environmental modifications (ramps, soft bedding) and physiotherapy as advised by a veterinarian.​

7. Common Dental Diseases in Male Cats

Dental disease, especially gingivitis and periodontal disease, affects a majority of adult cats and is not limited to one gender but is often very pronounced in males with poor oral care.​
Signs include bad breath, drooling, difficulty chewing, yellow or brown tartar, red gum lines and sometimes loose or missing teeth; prevention involves regular dental checkups, professional scaling when necessary and at‑home measures like dental diets or vet‑approved dental treats.​

8. Is Your Pet at Risk of Developing These Common Cat Health Problems?

The risk of most chronic diseases increases with age; senior cats are especially prone to kidney disease, hyperthyroidism, arthritis, dental disease and some cancers.​

In India, lifestyle is equally important: indoor cats face more obesity and behavioural issues, while outdoor and community cats are at higher risk of parasites, trauma, anaemia and viral infections like FIV/FeLV.​

9. Early Symptoms of Hyperthyroidism in Cats

Common early signs are weight loss despite good appetite, increased thirst and urination, hyperactivity, restlessness and sometimes vomiting or diarrhoea.​ 

Untreated hyperthyroidism can strain the heart and kidneys, so blood tests and early treatment are essential to protect a cat’s long‑term health.​

10. Recognizing Flea Bite Hypersensitivity

Flea allergy dermatitis is one of the most common skin problems in cats and can occur even with very low flea numbers.​ 

Affected cats show intense itching, redness, small bumps and hair loss, especially around the neck, back and tail base, and usually need both flea control and anti‑itch or anti‑allergic treatment prescribed by a vet.​

11. Reproductive System Infections and Complications

Unspayed female cats are at risk of pyometra (a life‑threatening uterine infection), metritis, mastitis and mammary tumours, especially after repeated heats and pregnancies.​ 

Signs include lethargy, fever, vaginal discharge, increased thirst, frequent or painful urination and enlarged abdomen; these conditions often require urgent surgery and intensive care.​

12. Signs of Periodontal Disease Affecting Gums and Teeth

Gingivitis and periodontal disease start with plaque and tartar buildup and progress to gum inflammation, tooth root damage and tooth loss.​ 

Watch for bad breath, red gum margins, yellow or brown tartar, drooling, pawing at the mouth or dropping food; early dental cleaning and home care can prevent tooth loss and reduce the risk of kidney and heart complications.​

13. Urinary Tract Infections (UTIs) and Cystitis in Cats

Cats with UTIs or feline idiopathic cystitis may strain to urinate, pass small amounts frequently, cry while urinating, have blood in urine or start peeing outside the litter box.​ 

Middle‑aged, overweight, stressed and mostly indoor cats are at higher risk, and male cats are more at risk of complete blockage which is an immediate emergency.​

14. Identifying Joint and Mobility Disorders

Joint issues may come from arthritis, past trauma, ligament injuries or weight‑related strain.​ 

Cats with mobility problems may show a stiff gait, reluctance to jump, difficulty climbing stairs, reduced play and grooming, or sudden lameness; sudden inability to use the hind legs can also be linked to severe heart disease and needs emergency care.​

15. Common Symptoms of Anaemia in Cats

Anaemia can result from parasites, chronic disease, blood loss, bone marrow disorders or viral infections like FeLV.​
Typical signs of anaemia in cats are pale gums, lethargy, rapid breathing, weakness and poor appetite; moderate to severe anaemia is dangerous and needs immediate diagnostic workup and treatment.​

16. Understanding Heart Murmurs and Cardiac Dysrhythmia in Cats

Heart murmurs and irregular heart rhythms (dysrhythmias) can be caused by congenital heart disease, cardiomyopathy, anaemia, hyperthyroidism or severe systemic illness.​
Cats with significant heart disease may show rapid or laboured breathing, open‑mouth breathing, fainting episodes, sudden hind‑leg weakness or cold limbs, and require urgent evaluation with chest imaging and ECG.​ 

17. Common Parasites in Cats and Their Impact on Health

Cats can be affected by internal parasites like roundworms, hookworms, tapeworms and protozoa, as well as external parasites like fleas, ticks and mites.​
Parasites can cause diarrhoea, vomiting, weight loss, anaemia, poor coat quality, intense itching, skin infections and even transmission of disease to humans; regular deworming and flea/tick control are key preventive measures.​ 

18. Feline Viral Infections (FIV & FeLV)

Feline immunodeficiency virus (FIV) and feline leukaemia virus (FeLV) are important retroviral infections in cats, especially in outdoor or fighting intact males and unvaccinated cats.​
These viruses weaken the immune system, leading to recurrent infections, anaemia, cancers, weight loss and chronic ill‑health; screening tests, vaccination (for FeLV where recommended), keeping cats indoors and neutering greatly reduces risk.​

19. Cat Bite Injuries and Risks

Cat bite wounds are often small punctures that can quickly become infected, leading to painful abscesses beneath the skin. Symptoms include swelling, pain, lethargy, limping, and fever. Prompt veterinary care with wound cleaning, antibiotics, and sometimes abscess drainage is vital to prevent serious infections.

Cat bites can transmit bacteria like Pasteurella and Bartonella (cat scratch disease), and rarely, rabies. Early treatment and careful monitoring reduce complications and protect y

 

20. Constipation and Gut Issues in Cats

Constipation in cats causes hard, dry stools and difficulty passing them, often due to dehydration, low fiber diets, stress, or underlying illness. It is most common in older cats but can affect all ages. Symptoms include straining, abdominal discomfort, decreased appetite, and lethargy.

Gut issues may also arise from blockages, arthritis pain, or chronic diseases like kidney problems. Treatment focuses on hydration, dietary fiber, exercise, and veterinary care, including laxatives or medications for severe cases. 

How to Keep Cats Healthy?

Core preventive steps include timely vaccinations, routine deworming, year‑round flea and tick control, spaying/neutering and yearly (or twice‑yearly for seniors) health checkups with basic blood and urine tests.​ 

Balanced, age‑appropriate nutrition, maintaining a healthy weight, providing fresh water, environmental enrichment and prompt veterinary attention at the first sign of illness help prevent or detect most problems early.​ 

Complications and Behaviour of Cats with Specific Illness

Sick cats often show non‑specific behaviours like hiding, reduced interaction, changes in grooming, aggression when touched, or changes in sleep and litter‑box patterns.​ 

Complications of untreated disease can include organ damage (kidneys, heart, liver), chronic pain, weight loss, poor quality of life and, in emergencies like urinary blockage or pyometra, sudden death if not treated in time.​ 

You Can Reduce Your Cat’s Health Risks

Understanding the common health problems in cats by gender, neutering status, and age empowers cat parents to provide timely care. Early detection and preventive measures dramatically improve outcomes, ensuring a longer, healthier life for your feline companion. Regular veterinary visits, a safe environment, and attentive observation are key to managing risks and keeping your cat happy and thriving at every life stage.

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