{"id":4171,"date":"2024-04-13T11:31:32","date_gmt":"2024-04-13T11:31:32","guid":{"rendered":"https:\/\/vetic.in\/blog\/?p=4171"},"modified":"2025-11-01T09:24:10","modified_gmt":"2025-11-01T09:24:10","slug":"polycystic-kidney-disease-in-persian-cats-the-leading-cause-of-kidney-failure-in-cats","status":"publish","type":"post","link":"https:\/\/vetic.in\/blog\/pet-health\/polycystic-kidney-disease-in-persian-cats-the-leading-cause-of-kidney-failure-in-cats\/","title":{"rendered":"Polycystic Kidney Disease in Persian Cats: The Leading Cause of Kidney Failure in Cats"},"content":{"rendered":"<p style=\"text-align: left;\"><span style=\"font-weight: 400;\">Some cat breeds are more prone to genetic disorders such as polycystic kidney disease as compared to others. According to <\/span><span style=\"font-weight: 400;\">UFAW<\/span><span style=\"font-weight: 400;\">, around 36% to 49% <a href=\"https:\/\/vetic.in\/blog\/pet-care\/how-to-take-care-of-your-persian-cat\/\">Persian cats<\/a> develop polycystic kidney disease (PKD) in their adulthood.\u00a0<\/span><\/p>\n<p style=\"text-align: left;\"><span style=\"font-weight: 400;\">Polycystic kidney disease or PKD can cause renal failure in cats when left untreated.\u00a0<\/span><\/p>\n<h2 style=\"text-align: left;\"><span style=\"font-weight: 400;\">What Is Polycystic Kidney Disease In Persian Cats?<\/span><\/h2>\n<p style=\"text-align: left;\"><img fetchpriority=\"high\" decoding=\"async\" class=\"alignnone size-full wp-image-4175\" src=\"https:\/\/vetic.in\/blog\/wp-content\/uploads\/2024\/04\/Polycystic-Kidney-Disease-In-Persian-Cat.jpg\" alt=\"What Is Polycystic Kidney Disease In Persian Cats? Polycystic kidney disease is a genetic condition that leads to the formation of multiple fluid-filled sacs or cysts in the cat\u2019s kidneys. The affected kittens are born with these cysts. The cyst growth is progressive which causes worsening kidney and liver functions in the affected Persian cats. Image by Vetic\" width=\"1890\" height=\"1063\" \/><\/p>\n<p style=\"text-align: left;\"><span style=\"font-weight: 400;\">Polycystic kidney disease is a genetic condition that leads to the formation of multiple fluid-filled sacs or cysts in the cat\u2019s kidneys. The affected kittens are born with these cysts but they are too small to be detected when the kittens are young.\u00a0<\/span><\/p>\n<p style=\"text-align: left;\"><span style=\"font-weight: 400;\">The growth of these cysts typically begins when the <\/span><a href=\"https:\/\/vetic.in\/blog\/cats\/is-your-cat-in-heat-9-obvious-signs-of-heat-in-cats\/\"><span style=\"font-weight: 400;\">persian cats reach breeding age<\/span><\/a><span style=\"font-weight: 400;\">. These cysts may become visible on scans once they cats are older than 5 months.\u00a0<\/span><\/p>\n<p style=\"text-align: left;\"><span style=\"font-weight: 400;\">The cyst growth is progressive which causes worsening kidney and liver functions in the affected Persian cats.\u00a0<\/span><\/p>\n<h2 style=\"text-align: left;\"><span style=\"font-weight: 400;\">Is Your Persian Cat At Risk Of Developing Feline Polycystic Kidney Disease?<\/span><\/h2>\n<p style=\"text-align: left;\"><img decoding=\"async\" class=\"alignnone size-full wp-image-4176\" src=\"https:\/\/vetic.in\/blog\/wp-content\/uploads\/2024\/04\/Is-Your-Persian-Cat-at-Risk-of-Developing-Polycystic-Kidney-Disease.jpg\" alt=\"vetic\u00ae Is Your Persian Cat at Risk of Developing Polycystic Kidney Disease? If you have a Persian kitten who is reaching breeding age, opt for an USG. Most cats who have PKD are born with these cysts in their kidneys that grow with time. DISEASE PROGRESSION Normal Kidney (normal cysts, 0-15) Kidney with APKD (mild cysts, 15-30) Kidney with APKD (moderate cysts, 30-45) Progressed APKD (severe cysts, 45+)\" width=\"1890\" height=\"1063\" \/><\/p>\n<p style=\"text-align: left;\"><span style=\"font-weight: 400;\">It is one of the most common and aggressive kidney diseases that is inherited by Persian cats. It is highly prevalent in Persian cats since it is an autosomal dominant trait. That means inheriting only one mutated gene is enough to cause polycystic kidney disease in cats.\u00a0<\/span><\/p>\n<p style=\"text-align: left;\"><span style=\"font-weight: 400;\">If you have a Persian cat who is reaching breeding age (older than 5 months), opt for an USG to ensure that their kidneys are free from cysts. Most cats who have PKD are born with these cysts in their kidneys that grow with time.\u00a0<\/span><\/p>\n<p style=\"text-align: left;\"><span style=\"font-weight: 400;\">Go in for <\/span><a href=\"https:\/\/vetic.in\/blog\/pet-care\/why-should-you-take-your-pet-for-regular-veterinary-check-ups\/\"><span style=\"font-weight: 400;\">preventive healthcare checkups<\/span><\/a><span style=\"font-weight: 400;\"> and tests such as USGs to ensure that your cat doesn\u2019t have any cysts in their kidneys. Along with USGs, the veterinarian will also recommend complete blood count, liver function and kidney function tests to check if there are any abnormalities present in the blood or serum.\u00a0<\/span><\/p>\n<h2 style=\"text-align: left;\"><span style=\"font-weight: 400;\">Your Persian Cat Has Cysts Or PKD. What To Do Now?<\/span><\/h2>\n<p style=\"text-align: left;\"><span style=\"font-weight: 400;\">Early diagnosis of polycystic kidney disease can help you manage your cat\u2019s symptoms. Just because a Persian cat or kitten has cysts in their kidneys it doesn\u2019t mean they will go into kidney failure rapidly. In many cases, the cysts enlarge very slowly and cats only <\/span><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/34822642\/\"><span style=\"font-weight: 400;\">begin to show signs of PKD<\/span><\/a><span style=\"font-weight: 400;\"> when they are around 7 years old.\u00a0<\/span><\/p>\n<p style=\"text-align: left;\"><span style=\"font-weight: 400;\">With early diagnosis and correct treatment, your veterinarian can help you slow the progression down. Your veterinarian will help you chalk out a proper diet, supplement and medicine plans so your cat lives a high quality and long life.\u00a0<\/span><\/p>\n<p style=\"text-align: left;\"><span style=\"font-weight: 400;\">Even with the earliest possible diagnosis, polycystic kidney disease is not curable or 100% preventable. However, you can definitely slow down the onset of the diseases and reduce a huge part of the signs and symptoms.\u00a0<\/span><\/p>\n<p style=\"text-align: left;\"><span style=\"font-weight: 400;\">If your cat has polycystic kidney disease you should not breed your cat. There is a 75% chance that your cat\u2019s babies will end up with polycystic kidney disease even if the other parent is free from the disease.\u00a0<\/span><\/p>\n<h2 style=\"text-align: left;\"><span style=\"font-weight: 400;\">What\u2019 are The Signs Polycystic Kidney Disease in Persian Cats?<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">Sadly, there is no standard treatment of polycystic kidney disease. The clinical signs are almost identical to that of <\/span><a href=\"https:\/\/vetic.in\/blog\/cats\/chronic-kidney-disease-in-cats-signs-causes-treatment-and-more\/\"><span style=\"font-weight: 400;\">chronic kidney disease (CKD) in cats.<\/span><\/a><span style=\"font-weight: 400;\"> The early signs of polycystic kidney disease in Persian cats include &#8211;<\/span><\/p>\n<ul>\n<li><span style=\"font-weight: 400;\">Vomiting<\/span><\/li>\n<li>Reduced appetite<\/li>\n<li>Increased thirst<\/li>\n<li>Frequent urination<\/li>\n<li>Weight loss<\/li>\n<\/ul>\n<p>Since the signs are often confusing and similar to other digestive issues and kidney conditions, the veterinarian should run a complete set of diagnostic tests including advanced ultrasound to check the health of the kidneys, especially, if the candidate is related to the Persian breed.<\/p>\n<h2 style=\"text-align: left;\"><span style=\"font-weight: 400;\">How is Polycystic Kidney Disease In Persian Cats Diagnosed<\/span><\/h2>\n<p>Even with modern DNA testing and blood and biochemistry tests it can&#8217;t be confirmed that a Persian cat or kitten showing signs similar to the early signs of Polycystic Kidney Disease actually has cysts in their kidneys.<\/p>\n<p>These cysts can be miniscule, smaller than the size of grapes. A cat can have one larger cyst or a collection of 20 2mm ones, the diagnosis is the same!<\/p>\n<p>The only way to diagnose Polycystic Kidney Disease in any cat is via ultrasound or USG. If your Persian cat is being <a href=\"https:\/\/vetic.in\/blog\/pet-health\/why-is-your-cat-vomiting-cat-vomit-colours-difference-from-regurgitation-diagnosis-and-treatment\/\">lethargic, throwing up or experiencing anorexia<\/a>, it&#8217;s a good idea to talk to your veterinarian about schedule a USG without delay.<\/p>\n<p>Early diagnosis of the disease can help you manage the quality of your pet&#8217;s life.<\/p>\n<h2 style=\"text-align: left;\"><span style=\"font-weight: 400;\">What\u2019s The Treatment For Polycystic Kidney Disease in Persian Cats?<\/span><\/h2>\n<p style=\"text-align: left;\"><img decoding=\"async\" class=\"alignnone size-full wp-image-4177\" src=\"https:\/\/vetic.in\/blog\/wp-content\/uploads\/2024\/04\/Treatment-Of-Polycystic-Kidney-Disease-In-Persian-Cats.jpg\" alt=\"Treatment Of Polycystic Kidney Disease In Persian Cats Kidney Food Liver Support Medicines Fluid Therapy Anti-Nausea Medication Kidney Support Medication Phosphorus Binders Kidney food and supplements are part of your cat\u2019s treatment plan\" width=\"1890\" height=\"1063\" \/><\/p>\n<p style=\"text-align: left;\"><span style=\"font-weight: 400;\">The treatment is similar to CKD in cats as well. It focuses on management and reduction of the signs such as vomiting, anorexia, dehydration and pain.\u00a0<\/span><\/p>\n<p style=\"text-align: left;\"><span style=\"font-weight: 400;\">Treatment of polycystic kidney disease in Persian Cats include &#8211;<\/span><\/p>\n<ul style=\"text-align: left;\">\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Therapeutic diets (kidney food)<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Fluid therapy<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Kidney support medication<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Liver support medicines<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Medicines for vomiting and nausea<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Phosphorus binders\u00a0<\/span><\/li>\n<\/ul>\n<p style=\"text-align: left;\"><span style=\"font-weight: 400;\">Kidney food and supplements ARE part of your cat\u2019s treatment plan. In fact, they play the central role in the management of all the clinical signs of PKD in cats.\u00a0<\/span><\/p>\n<h2 style=\"text-align: left;\"><span style=\"font-weight: 400;\">Prognosis Of Polycystic Kidney Disease In Persian Cats<\/span><\/h2>\n<p style=\"text-align: left;\"><span style=\"font-weight: 400;\">Any cat with polycystic kidney disease needs frequent <a href=\"https:\/\/vetic.in\/blog\/pet-care\/blood-tests-for-dogs-and-cats-the-complete-guide-for-pet-parents\/\">USG, and blood<\/a> tests to check the progress of the disease.\u00a0<\/span><\/p>\n<p style=\"text-align: left;\"><span style=\"font-weight: 400;\">Frequent health checkups are mandatory for all Persians with traits of polycystic kidney disease to monitor the disease progress.\u00a0<\/span><\/p>\n<p style=\"text-align: left;\"><span style=\"font-weight: 400;\">The veterinarian will adjust the medicine doses and diet according to their updated health status.\u00a0<\/span><\/p>\n<p style=\"text-align: left;\"><span style=\"font-weight: 400;\">Persians with early-detected PKD can live a long life since the treatment can slow the progress of the disease.\u00a0<\/span><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Some cat breeds are more prone to genetic disorders such as polycystic kidney disease as compared to others. According to UFAW, around 36% to 49% Persian cats develop polycystic kidney&hellip;<\/p>\n","protected":false},"author":9,"featured_media":4174,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_monsterinsights_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0,"_lmt_disableupdate":"no","_lmt_disable":"","footnotes":""},"categories":[64],"tags":[9,112,137,136],"class_list":["post-4171","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-pet-health","tag-cat","tag-cat-disease","tag-cat-health","tag-cat-treatment"],"aioseo_notices":[],"_links":{"self":[{"href":"https:\/\/vetic.in\/blog\/wp-json\/wp\/v2\/posts\/4171","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/vetic.in\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/vetic.in\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/vetic.in\/blog\/wp-json\/wp\/v2\/users\/9"}],"replies":[{"embeddable":true,"href":"https:\/\/vetic.in\/blog\/wp-json\/wp\/v2\/comments?post=4171"}],"version-history":[{"count":7,"href":"https:\/\/vetic.in\/blog\/wp-json\/wp\/v2\/posts\/4171\/revisions"}],"predecessor-version":[{"id":6764,"href":"https:\/\/vetic.in\/blog\/wp-json\/wp\/v2\/posts\/4171\/revisions\/6764"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/vetic.in\/blog\/wp-json\/wp\/v2\/media\/4174"}],"wp:attachment":[{"href":"https:\/\/vetic.in\/blog\/wp-json\/wp\/v2\/media?parent=4171"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/vetic.in\/blog\/wp-json\/wp\/v2\/categories?post=4171"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/vetic.in\/blog\/wp-json\/wp\/v2\/tags?post=4171"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}